This study highlights the significance of technological orientation in developing Nigerian university-based entrepreneurial ecosystem. The result of this research shows that technological orientation is heavily depended on cost of technology, maintenance of technology and ICT awareness. Constructivist grounded theory, a qualitative typological approach, was employed to uncover the nuances in the dimensions of Technological orientation. Extrinsically, interview data were collected from respondents in Nigerian universities in two stages to identify 7 initial themes and 3 macro-themes. The perceptions of the respondents about Technological orientation was discussed contextually. The emergence of the dimension underscores the obliviousness and low paradigmatic conceptualization of technological entrepreneurial ecosystem in the research ambience. The research inferences are given for future substantive development of technologically improved university-based entrepreneurial ecosystem.