This article underscores the necessity of addressing the inconsistencies and mixed results inherent in prior entrepreneurial ecosystem research categories and constructs. During the process of analysis and coding, some of the emergent categories associated with the development of University-based entrepreneurial ecosystem (U-BEE) are in consonant with prior research, especially from the developed countries. A Constructivist grounded theory method was employed to decipher the essence of Technological diffusion in the development of University-based entrepreneurial ecosystem (U-BEE) in Nigerian universities. Empirically, observational data and interviews were employed in 3 stages, identifying 3 initial categories and 7 macro-themes. The respondents' perceptions about Technological diflUsion was explicated elaborately in cognizance of the complexities of the research ambience. The dimensional nuances in the emergence of the constructs reflects the convoluted complexities in developing UBEE in Nigerian context. The implication of the research in relation to future theoretical improvement are concisely delineated.